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Antioxidant effect of grape molasses in rat heart tissues
Kıran, Tuğba Raika; Otlu, Önder; Karabulut, Ercan; Pakdemirli, Ahu; Özcan, Nermin (Medicine Science, 2019)Grape molasses, which is rich in mineral substances such as flavonoids, polyphenol, antioxidants, iron, calcium, phosphorus, potassium, and magnesium is a natural nutrient, that is concentrated with boiling without adding ... -
Artificial Circulation System Algorithm: A Novel Bio-Inspired Algorithm
Özcan, Nermin; Utku, Semih; Berber, Tolga (Tech Science Press, 2024)Metaheuristics are commonly used in various fields, including real-life problem-solving and engineering applications. The present work introduces a novel metaheuristic algorithm named the Artificial Circulatory System ... -
A Comparative Study of Metaheuristic Feature Selection Algorithms for Respiratory Disease Classification
Gürkan Kuntalp, Damla; Özcan, Nermin; Düzyel, Okan; Kababulut, Fevzi Yasin; Kuntalp, Mehmet (Multidisciplinary Digital Publishing Institute (MDPI), 2024)The correct diagnosis and early treatment of respiratory diseases can significantly improve the health status of patients, reduce healthcare expenses, and enhance quality of life. Therefore, there has been extensive interest ... -
Electrochemical cardiac troponin I immunosensor based on nitrogen and boron-doped graphene quantum dots electrode platform and Ce-doped SnO2/SnS2 signal amplification
Karaman, Onur; Özcan, Nermin; Karaman, Ceren; Yola, Bahar Bankoğlu; Atar, Necip; Yola, Mehmet Lütfi (Elsevier, 2022)The detection of acute myocardial infarction directly depends on the concentration of the cardiac troponin I (CTnI) in human blood plasma. In this study, the sensitive, selective, and fast sandwich-type electrochemical ... -
Electrochemical detection of amyloid-β protein by delaminated titanium carbide MXene/multi-walled carbon nanotubes composite with molecularly imprinted polymer
Özcan, Nermin; Medetalibeyoğlu, Hilal; Akyıldırım, Onur; Atar, Necip; Yola, Mehmet Lütfi (Elsevier, 2020)Amyloid-β protein, a polypeptide, is known as the reason of neuronal death and is widely recognized as a biomarker of Alzheimer's disease. In this study, a simple and rapid electrochemical biosensor based on delaminated ... -
Electrochemical Tau Protein Immunosensor Based on MnS/GO/PANI and Magnetite-incorporated Gold Nanoparticles
Yola, Bahar Bankoğlu; Karaman, Ceren; Özcan, Nermin; Atar, Necip; Polat, İlknur; Yola, Mehmet Lütfi (Wiley, 2022)Herein, electrochemical tau protein immunosensor based on manganese sulfide nanoparticles/graphene oxide/polyaniline (MnS/GO/PANI) and magnetite-incorporated gold nanoparticles (AuNPs@Fe3O4) was constructed. After the ... -
A New Shapley-Based Feature Selection Method in a Clinical Decision Support System for the Identification of Lung Diseases
Kababulut, Fevzi Yasin; Gürkan Kuntalp, Damla; Düzyel, Okan; Özcan, Nermin; Kuntalp, Mehmet (MDPI, 2023)The aim of this study is to propose a new feature selection method based on the class-based contribution of Shapley values. For this purpose, a clinical decision support system was developed to assist doctors in their ... -
A novel electrochemical lung cancer biomarker cytokeratin 19 fragment antigen 21-1 immunosensor based on Si3N4/MoS2incorporated MWCNTs and core-shell type magnetic nanoparticles
Yola, Mehmet Lütfi; Atar, Necip; Özcan, Nermin (Royal Society of Chemistry, 2021)Lung cancer is one of deadliest and most life threatening cancer types. Cytokeratin 19 fragment antigen 21-1 (CYFRA 21-1) is a significant biomarker for the diagnosis of non-small cell lung cancer (NSCLC). Due to these ...