Yazar "Pradhan, Ajay" için listeleme
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The brominated flame retardants TBECH and DPTE alter prostate growth, histology and gene expression patterns in the mouse
Bereketoğlu, Ceyhun; Modig, Carina; Pradhan, Ajay; Andersson, Patrik L.; Stasinopoulou, Sotiria; Mitsiou, Dimitra J.; Alexis, Michael N.; Olsson, Per-Erik (Elsevier, 2021)The brominated flame retardants (BFRs), 1,2-dibromo-4-(1,2 dibromoethyl)cyclohexane (TBECH) and 2,3-dibromopropyl-2,4,6-tribromophenyl ether (DPTE) bind to the androgen receptor (AR). in vitro bioassays have shown that ... -
The food preservative ethoxyquin impairs zebrafish development, behavior and alters gene expression profile
Pradhan, Ajay; Bereketoğlu, Ceyhun; Martin, Lea; Duhagon, Justine; Olsson, Per-Erik (Pergamon-Elsevier Science Ltd, 2020)In the present study, we investigated the detrimental effects of ethoxyquin (EQ) on zebrafish embryonic development using different endpoints including lethality, malformations, locomotion and gene expression. EQ is primarily ... -
In silico and in vitro assessment of androgen receptor antagonists
Serçinoğlu, Onur; Bereketoğlu, Ceyhun; Olsson, Per-Erik; Pradhan, Ajay (Elsevier, 2021)There is a growing concern for male reproductive health as studies suggest that there is a sharp increase in prostate cancer and other fertility related problems. Apart from lifestyle, pollutants are also known to negatively ... -
Nonsteroidal anti-inflammatory drugs (NSAIDs) cause male-biased sex differentiation in zebrafish
Bereketoğlu, Ceyhun; Pradhan, Ajay; Olsson, Per-Erik (Elsevier, 2020)Nonsteroidal anti-inflammatory drugs (NSAIDs) are widely used pharmaceuticals to treat pain, fever and inflammation. NSAIDs are also known to have many side effects including adverse effects on reproduction in both humans ... -
Transcriptomic analysis of nonylphenol effect on Saccharomyces cerevisiae
Bereketoğlu, Ceyhun; Nacar, Gözde; Sarı, Tuğba; Mertoğlu, Bülent; Pradhan, Ajay (PeerJ Inc., 2021)Nonylphenol (NP) is a bioaccumulative environmental estrogen that is widely used as a nonionic surfactant. We have previously examined short-term effects of NP on yeast cells using microarray technology. In the present ...
