dc.contributor.author | Medetalibeyoğlu, Hilal | |
dc.contributor.author | Kotan, Gül | |
dc.contributor.author | Atar, Necip | |
dc.contributor.author | Yola, Mehmet Lütfi | |
dc.date.accessioned | 2020-11-25T10:12:07Z | |
dc.date.available | 2020-11-25T10:12:07Z | |
dc.date.issued | 2020 | en_US |
dc.identifier.citation | Medetalibeyoglu, H., Kotan, G., Atar, N., & Yola, M. L. (2020). A novel and ultrasensitive sandwich-type electrochemical immunosensor based on delaminated MXene@AuNPs as signal amplification for prostate specific antigen (PSA) detection and immunosensor validation. Talanta, 220(1), 121403.
https://doi.org/10.1016/j.talanta.2020.121403 | en_US |
dc.identifier.uri | https://doi.org/10.1016/j.talanta.2020.121403 | |
dc.identifier.uri | https://hdl.handle.net/20.500.12508/1394 | |
dc.description.abstract | In this study, an ultra-sensitive electrochemical immunosensor for PSA detection was designed. Firstly, gold nanoparticles (AuNPs)/p-aminothiophenol (ATP) functionalized graphene oxide (GO) composite (AuNPs- ATPGO) was constructed and modified to glassy carbon electrode (AuNPs-ATPGO/GCE). AuNPs-ATPGO/GCE was utilized as immunosensor platform to increase the amount of PSA antibody1 (Ab1). After that, self- assembled delaminated MXene-gold nanoparticles (d-Ti3C2TX MXene@AuNPs) was used to label PSA seconder antibody2 (Ab2) as signal amplification. The prepared AuNPs-ATPGO, d-Ti3C2TX MXene@AuNPs and electro-chemical immunosensor was charecterized by electrochemical impedance spectroscopy (EIS), cyclic voltam-metry (CV), scanning electron microscope (SEM), x-ray diffraction (XRD) method, x-ray photoelectron spectroscopy (XPS), transmission electron microscopy (TEM), fourier transform infrared spectroscopy (FTIR). The linearity range and detection limit (LOD) were obtained as 0.01–1.0 pg mL-1 and 3.0 fg mL-1, respectively. | en_US |
dc.language.iso | eng | en_US |
dc.publisher | Elsevier | en_US |
dc.rights | info:eu-repo/semantics/closedAccess | en_US |
dc.subject | Prostate-specific antigen (PSA) | en_US |
dc.subject | Gold nanoparticles/graphene oxide composite | en_US |
dc.subject | d-Ti3C2TX MXene@AuNPs | en_US |
dc.subject | Immunosensor | en_US |
dc.subject | Validation | en_US |
dc.subject.classification | Chemistry | |
dc.subject.classification | Analytical | |
dc.subject.classification | Titanium Carbide | Sodium-ion Batteries | Ion Storage | |
dc.subject.other | Nanoparticles | |
dc.subject.other | Composites | |
dc.subject.other | Catalysis | |
dc.subject.other | Carbon | |
dc.subject.other | Sensor | |
dc.subject.other | Antigens | |
dc.subject.other | Cyclic voltammetry | |
dc.subject.other | Fiber optic sensors | |
dc.subject.other | Fourier transform infrared spectroscopy | |
dc.subject.other | Glass membrane electrodes | |
dc.subject.other | Gold nanoparticles | |
dc.subject.other | Graphene | |
dc.subject.other | High resolution transmission electron microscopy | |
dc.subject.other | Immunosensors | |
dc.subject.other | Metal nanoparticles | |
dc.subject.other | Scanning electron microscopy | |
dc.subject.other | X ray photoelectron spectroscopy | |
dc.subject.other | Detection limits | |
dc.subject.other | Electrochemical immunosensors | |
dc.subject.other | Functionalized graphene | |
dc.subject.other | Glassy carbon electrodes | |
dc.subject.other | Linearity range | |
dc.subject.other | Signal amplifications | |
dc.subject.other | Ultra sensitives | |
dc.subject.other | Electrochemical impedance spectroscopy | |
dc.title | A novel and ultrasensitive sandwich-type electrochemical immunosensor based on delaminated MXene@AuNPs as signal amplification for prostate specific antigen (PSA) detection and immunosensor validation | en_US |
dc.type | article | en_US |
dc.relation.journal | Talanta | en_US |
dc.contributor.department | Mühendislik ve Doğa Bilimleri Fakültesi -- Biyomedikal Mühendisliği Bölümü | en_US |
dc.identifier.volume | 220 | en_US |
dc.identifier.issue | 1 | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
dc.contributor.isteauthor | Yola, Mehmet Lütfi | |
dc.relation.index | Web of Science - Scopus - PubMed | en_US |
dc.relation.index | Web of Science Core Collection - Science Citation Index Expanded | |