dc.contributor.author | Şener, Serpil | |
dc.contributor.author | Karaman, Ülkü | |
dc.contributor.author | Kıran, Tuğba Raika | |
dc.contributor.author | Çolak, Cemil | |
dc.contributor.author | Aslan, Ali | |
dc.contributor.author | Direkel, Şahin | |
dc.date.accessioned | 2021-07-08T13:40:58Z | |
dc.date.available | 2021-07-08T13:40:58Z | |
dc.date.issued | 2020 | en_US |
dc.identifier.citation | Sener, S., Karaman, U., Kiran, T. R., Colak, C., Aslan, A., & Direkel, S. (2020). Role of Adenosine Deaminase in Patients with Erythematotelangiectatic Rosacea and Demodex folliculorum Positivity. Iranian journal of parasitology, 15(4), 596–601. https://doi.org/10.18502/ijpa.v15i4.4870 | en_US |
dc.identifier.uri | https://doi.org/10.18502/ijpa.v15i4.4870 | |
dc.identifier.uri | https://hdl.handle.net/20.500.12508/1858 | |
dc.description.abstract | Background: Adenosine deaminase (ADA) is an aminohydrolase involved in the catabolism of purine nucleotides and irreversibly deaminizes adenosine and deoxy-adenosine to inosine and deoxyinosine. ADA enzyme deficiency results in the loss of functional properties of B and T lymphocytes. Demodex species have been reported to be transmitted between humans through close contact and to play a role in the path-ogenesis of rosacea, acne vulgaris, perioral dermatitis, seborrhoeic dermatitis, micro-papillary-pruritic dermatitis and blepharitis. The present study aimed to compare serum ADA levels in D. folliculorum positive patients with the healthy control individu-als. Methods: Serum ADA levels were examined for 30 patients diagnosed with ery-thematotelangiectatic rosacea and 40 healthy individuals in Malatya Inonu University in 2017. Standardized skin surface biopsy (SSSB) method was used to diagnose D. folliculorum. A significant decrease was found in the ADA levels of Demodex-positive rosacea patients when compared to the control group. Results: ADA levels were decreased in the Demodex-positive group. The mean ADA level in patient group was significantly lower than the mean in the control group (P<0.001). There was no significant difference between the patient and control groups in terms of age and gender. Conclusion: During and after treatment of Demodex-positive rosacea patients, de-termination of ADA levels may give more detailed information on the immune mechanisms. | en_US |
dc.language.iso | eng | en_US |
dc.publisher | Tehran University of Medical Sciences | en_US |
dc.relation.isversionof | 10.18502/ijpa.v15i4.4870 | en_US |
dc.rights | info:eu-repo/semantics/openAccess | en_US |
dc.subject | Adenosine deaminase level | en_US |
dc.subject | Demodex folliculorum | en_US |
dc.subject | Ervthematotelangiectatic rosacea | en_US |
dc.subject.classification | Parasitology | |
dc.subject.classification | Demodex | |
dc.subject.classification | Demodicosis | |
dc.subject.classification | Blepharitis | |
dc.subject.other | Human demodicosis | |
dc.subject.other | Serum | |
dc.subject.other | Brevis | |
dc.subject.other | Mites | |
dc.subject.other | Adenosine deaminase | |
dc.subject.other | Ammonia | |
dc.subject.other | Acne vulgaris | |
dc.subject.other | Adenosine deaminase deficiency | |
dc.subject.other | Adult | |
dc.subject.other | Blepharitis | |
dc.subject.other | Clinical article | |
dc.subject.other | Controlled study | |
dc.subject.other | Cross-sectional study | |
dc.subject.other | Demodicosis | |
dc.subject.other | Dermatitis | |
dc.subject.other | Feces analysis | |
dc.subject.other | Female | |
dc.subject.other | Human | |
dc.subject.other | Male | |
dc.subject.other | Observational study | |
dc.subject.other | Rosacea | |
dc.subject.other | Skin biopsy | |
dc.title | Role of Adenosine Deaminase in Patients with Erythematotelangiectatic Rosacea and Demodex folliculorum Positivity | en_US |
dc.type | article | en_US |
dc.relation.journal | Iranian Journal of Parasitology | en_US |
dc.contributor.department | Mühendislik ve Doğa Bilimleri Fakültesi -- Biyomedikal Mühendisliği Bölümü | en_US |
dc.identifier.volume | 15 | en_US |
dc.identifier.issue | 4 | en_US |
dc.identifier.startpage | 596 | en_US |
dc.identifier.endpage | 601 | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
dc.contributor.isteauthor | Kıran, Tuğba Raika | |
dc.relation.index | Web of Science - Scopus - PubMed | en_US |
dc.relation.index | Web of Science Core Collection - Science Citation Index Expanded | |